Different screen resolutions and scale settings

Is there any general guidance or technical document on how to force my TMS components to display properly for different screen resolutions and user selected scale settings?

What looks perfect on my "1920x1080 Scale=100%" monitor looks very different when Scale=150% and greater, and often is difficult to use, tiny fonts in my string grids, with areas inaccessible, even with scroll bars, and so on.

My main form is set Scaled=true. I am using Segoe UI fonts everywhere.

Any suggestions will be welcome.