Yes, it's possible. You have to add your own routing logic when calling Route:
The key is the anonymous method in the Route parameter:
Echo.Route(
procedure(Log: TEchoLog; Node: TEchoNode; var Route: boolean)
begin
if SameText(Log.EntityClass, 'AppEntities.TEchoInvoice')
and (Node.Id = 'Client1') then
Route := false;
end;
);
You have to implement your own logic to tell Echo if that specific record should be routed to that specific node.